工作经历
2012.7- 中国科学院国家数学与交叉科学中心生物医学部 助理研究员 2012.7- 中国科学院数学与系统科学研究院 助理研究员
主要成就
在Nature子刊、Nucleic Acids Research、Bioinformatics、Briefings in Bioinformatics等国际权威期刊以第一作者和通讯作者身份发表生物信息学相关领域论文18篇,第一作者14篇, 通讯作者10篇,发表论文目前共被引用302次,参编专著4部,获得授权专利1项,曾获国际网络博弈论大会最佳论文奖、中科院数学院院长奖学金、博时奖学金、永安期货奖学金、英达奖学金、第四届世界华人数学家大会新世界数学奖、美国数学建模竞赛国际一等奖等荣誉,主持或以骨干身份参与 国家自然科学基金重大研究计划、国家自然科学基金青年基金等11项重要项目.
著作成果
Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA Scientific Reports:2015,5:13186 (SCI 影响因子5.578, nature旗下,独立作者) Drug–target interaction prediction: databases, web servers and computational models Briefings in Bioinformatics: 2015 ,In press (SCI 影响因子9.617,第一作者和通讯作者) RBMMMDA: predicting multiple types of disease-microRNA associations Scientific Reports:2015,5: 13877 (SCI 5.578, nature旗下,第一作者和通讯作者) Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity Scientific Reports. 2015 5:11338 (SCI 5.578, nature旗下,第一作者和通讯作者) Distributed Image Understanding with Semantic Dictionary and Semantic Expansion Neurocomputing:2015,In press (SCI 2.083) Semi-supervised learning for potential human microRNA-disease associations inference Scientific Reports. 2014,4:5501 (SCI 5.078, nature旗下,被引用10次,第一作者和通讯作者) 2012-2013运筹学学科发展报告 中国运筹学会.中国科学技术出版社:,2014 ASDCD: Antifungal Synergistic Drug Combination Database PLOS ONE:2014,9(1): e86499 (SCI 3.73 第一作者). Large Scale Image Understanding with Non-convex Multi-task Learning The 2014 5th International Conference on Game Theory for Networks:2014,Best Paper Award. Novel human lncRNA-disease association inference based on lncRNA expression profiles Bioinformatics:2013,29(20),2617-2624 (SCI 5.323, 2/47 in Mathematical & Computational Biology,被引用12次,第一作者和通讯作者) A computational framework to infer human disease-associated long noncoding RNAs PLOS ONE:2014,9(1): e84408 (SCI 3.73,被引用13次). LncRNADisease: a database for long-non-coding RNA-associated diseases Nucleic Acids Research:2013,41(Database issue),D983--D986 (SCI: 8.026, 26/289 in Biochemistry and Molecular Biology,被引用120次). Drug-Target Interaction Prediction by Random Walk on the Heterogeneous Network Molecular BioSystems:2012,8(7)1970-1978 (SCI 3.825,被引用52次 Top ten most accessed articles),in June 2012;Top 10% of the most highly cited articles published in the latest Impact Factor window (2011-2012), 第一作者). RWRMDA: predicting novel human microRNA-disease associations Molecular BioSystems:2012,8(10),1970-1978 (SCI 3.825, 被引用33次,第一作者). Prediction of disease-related interactions between microRNAs and environmental factors based on a semi-supervised classifier PLoS ONE:2012,7(8),e43425 (SCI 4.092,第一作者,被引用12次,第一作者) A novel candidate disease genes prioritization method based on module partition and rank fusion OMICS: A Journal of Integrative Biology:2010,14 (4),337-356 (SCI 3.17,被引用13次,第一作者和通讯作者). 多阶段多目标多部门应急决策模型 系统工程理论与实践:2010,30(11),1977-1985 (EI 0.896,被引用23次,第一作者和通讯作者). NRWRH for drug target prediction The 4th International conference on computational Systems Biology:2010,13,219-226 (ISTP, 第一作者和通讯作者). Modularized random walk with restart for candidate disease genes prioritization Optimization and Systems Biology:2009,11,353-360 (ISTP, 第一作者和通讯作者).